Toin H van Kuppevelt Selected Research

Sulfates (Sulfates, Inorganic)

6/2010	Heparan sulfates in the lung: structure, diversity, and role in pulmonary emphysema.
3/2007	In vivo degradation of heparan sulfates in the glomerular basement membrane does not result in proteinuria.
8/2006	Aberrant heparan sulfate profile in the human diabetic kidney offers new clues for therapeutic glycomimetics.

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Toin H van Kuppevelt Research Topics

Disease

38	Neoplasms (Cancer) 01/2021 - 06/2003
12	Proteinuria 04/2023 - 08/2006
9	Ovarian Neoplasms (Ovarian Cancer) 04/2017 - 10/2007
8	Albuminuria 01/2021 - 08/2006
7	Wounds and Injuries (Trauma) 09/2023 - 01/2005
6	Neoplasm Metastasis (Metastasis) 03/2020 - 03/2004
6	Carcinoma (Carcinomatosis) 04/2017 - 10/2007
6	Diabetic Nephropathies (Diabetic Nephropathy) 11/2016 - 08/2006
5	Carcinogenesis 04/2015 - 05/2010
5	Pathologic Processes 11/2014 - 05/2010
5	Inflammation (Inflammations) 01/2012 - 03/2004
4	Fibrosis (Cirrhosis) 08/2021 - 01/2015
4	Glomerulonephritis 01/2021 - 04/2007
4	Cicatrix (Scar) 05/2017 - 04/2004
4	Melanoma (Melanoma, Malignant) 09/2010 - 06/2003
3	Infections 01/2022 - 11/2013
3	Emphysema 01/2021 - 03/2008
3	Alzheimer Disease (Alzheimer's Disease) 05/2012 - 10/2008
3	Ehlers-Danlos Syndrome (Syndrome, Ehlers-Danlos) 04/2008 - 04/2004
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2023 - 01/2021
2	Hypoxia (Hypoxemia) 01/2021 - 01/2005
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2021 - 08/2006
2	Spinal Dysraphism (Spina Bifida) 01/2021 - 05/2010
2	Diaphragmatic Hernia 11/2018 - 07/2013
2	Glioblastoma (Glioblastoma Multiforme) 01/2018 - 01/2012
2	Hypertrophy 03/2016 - 04/2014
2	Mucopolysaccharidosis I (Hurler Syndrome) 01/2016 - 12/2014
2	Mucopolysaccharidoses 01/2016 - 03/2011
2	Hepatocellular Carcinoma (Hepatoma) 04/2015 - 05/2010
2	Breast Neoplasms (Breast Cancer) 01/2015 - 02/2010
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2015 - 07/2007
2	Bladder Exstrophy (Exstrophy, Bladder) 09/2014 - 01/2008
2	Gastroschisis 03/2013 - 12/2008
2	Amyloid Plaque 05/2012 - 12/2010
2	Amyloidosis 12/2010 - 10/2008
2	False Aneurysm (Pseudoaneurysm) 11/2010 - 07/2010
2	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 04/2010 - 02/2010
2	Adenocarcinoma 07/2009 - 10/2007
2	Nevus (Nevi) 03/2004 - 06/2003
1	Type 2 Diabetes Mellitus (MODY) 04/2023
1	Immunoglobulin Light-chain Amyloidosis 01/2023
1	Pain (Aches) 01/2022

Drug/Important Bio-Agent (IBA)

31	Heparitin Sulfate (Heparan Sulfate)IBA 04/2023 - 06/2003
18	GlycosaminoglycansIBA 01/2017 - 06/2003
15	Chondroitin Sulfates (Chondroitin Sulfate)IBA 03/2020 - 06/2003
14	CollagenIBA 01/2021 - 04/2004
14	EpitopesIBA 03/2016 - 06/2003
13	AntibodiesIBA 01/2021 - 06/2003
12	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2021 - 06/2003
12	Proteins (Proteins, Gene)FDA Link 01/2021 - 06/2003
10	Heparin (Liquaemin)FDA LinkGeneric 01/2023 - 11/2005
10	Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA 01/2021 - 03/2004
8	EnzymesIBA 12/2015 - 10/2007
7	Polysaccharides (Glycans)IBA 03/2016 - 08/2006
7	Dermatan SulfateIBA 07/2015 - 12/2008
6	heparanaseIBA 04/2023 - 12/2007
6	Proteoglycans (Proteoglycan)IBA 01/2021 - 04/2008
5	Biomarkers (Surrogate Marker)IBA 01/2017 - 10/2012
4	CytokinesIBA 01/2021 - 06/2003
4	LigandsIBA 01/2018 - 11/2005
4	AlbuminsIBA 04/2017 - 12/2012
3	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2023 - 12/2012
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2021 - 10/2007
3	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 08/2021 - 12/2007
3	ChemokinesIBA 01/2021 - 03/2004
3	LipidsIBA 01/2021 - 02/2009
3	Syndecan-1 (Syndecan 1)IBA 10/2015 - 02/2008
3	ChondroitinIBA 07/2015 - 06/2003
3	Sulfates (Sulfates, Inorganic)IBA 06/2010 - 08/2006
3	Amyloid beta-PeptidesIBA 04/2010 - 10/2008
2	Biocompatible Materials (Biomaterials)IBA 09/2023 - 01/2016
2	RNA (Ribonucleic Acid)IBA 01/2023 - 01/2018
2	DecorinIBA 01/2021 - 07/2009
2	InterferonsIBA 01/2021 - 02/2009
2	Immunoglobulin G (IgG)IBA 01/2021 - 05/2014
2	Matrix Metalloproteinases (MMPs)IBA 01/2019 - 04/2016
2	Streptozocin (Streptozotocin)FDA Link 11/2016 - 03/2016
2	CreatinineIBA 03/2016 - 02/2014
2	PolymersIBA 01/2016 - 07/2009
2	Periodic AcidIBA 12/2014 - 01/2005
2	Amyloid (Amyloid Fibrils)IBA 05/2012 - 01/2012
2	Peptides (Polypeptides)IBA 05/2012 - 04/2010
2	Racemases and Epimerases (Epimerases and Racemases)IBA 03/2011 - 07/2009
2	Collagen Type I (Type I Collagen)IBA 11/2010 - 07/2009
2	Fibrillin-1IBA 08/2009 - 03/2008
2	Transforming Growth Factor beta (TGF-beta)IBA 08/2009 - 01/2005
2	Heparinoids (Heparinoid)IBA 02/2008 - 04/2007
2	AcidsIBA 12/2007 - 03/2007
2	tenascin XIBA 02/2005 - 04/2004
1	Pioglitazone (Actos)FDA Link 04/2023
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 04/2023
1	2-chloro-5-nitrobenzanilideIBA 04/2023
1	Calcitonin Gene-Related PeptideIBA 01/2022
1	NeuropeptidesIBA 01/2022
1	ONO 1301IBA 08/2021
1	4- ((4- (((4- amino- 2,3,5,6- tetramethylanilino)acetyl)(methyl)amino)- 1- piperidinyl)methyl)benzamideIBA 08/2021
1	SodiumIBA 01/2021

Therapy/Procedure

10	Therapeutics 01/2019 - 08/2006
3	Drug Therapy (Chemotherapy) 01/2018 - 01/2015
2	Artificial Skin 08/2021 - 05/2017